The present invention relates to a phenol derivative and the preparationmethod anduse in medicine thereof, and particular to a phenol derivative represented bygeneralformula (A) or a stereoisomer, a solvate, a metabolite, a prodrug, apharmaceuticallyacceptable salt or a cocrystal thereof, a preparation method thereof, apharmaceuticalcomposition comprising the same, and use of the compound or composition of thepresent invention in the field of the central nervous system; wherein thedefinitions ofsubstituents in general formula (A) are the same as those in the Description.