Simona M. Ceccarelli,Aurelia Conte,Holger Kuehne,Bernd Kuhn,Werner Neidhart,Ulrike Obst Sander,Markus Rudolph
申请号：
US13666202
公开号：
US20130116234A1
申请日:
2012.11.01
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention provides novel compounds having the general formula (I)wherein R1, R2, R3, R4, R5, R6 and n are as described herein, compositions including the compounds and methods of using the compounds. The present compounds are useful as fatty-acid binding protein (FABP) 4 and/or 5 inhibitors and may be used for the treatment or prophylaxis of lipodystrophy, type 2 diabetes, dyslipidemia, atherosclerosis, liver diseases involving inflammation, steatosis and/or fibrosis, such as non-alcoholic fatty liver disease, in particular non-alcoholic steatohepatitis, metabolic syndrome, obesity, chronic inflammatory and autoimmune inflammatory diseases.
