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ANTIGÈNE CD49F FAVORISANT LA PROLIFÉRATION, LA PLURIPOTENCE ET LA REPROGRAMMATION DE CELLULES SOUCHES ADULTES PAR L'INTERMÉDIAIRE DE LA VOIE PI3K/AKT/GSK3
专利权人:
Kang Stem Holdings Co.; Ltd
发明人:
申请号:
EP11744922.3
公开号:
EP2537922A2
申请日:
2011.02.18
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention relates to a method for obtaining adult stem cells, which have a surface antigen of CD49f, excellent formation of spheres due to sphere formation and high expression of OCT4 and SOX2, from a cell source including stem cells, and a cell therapeutic agent containing adult stem cells obtained by the method or cells differentiated therefrom as an active ingredient.According to the present invention, adult stem cells derived from spheres are suitable for mass culture of adult stem cells because of more rapid growth thereof compared with stem cells obtained by a known adhesive culture method, have a specific surface antigen so as to be homogeneously obtained by using the specific surface antigen, and are useful for preparing a cell therapeutic agent using the same because of excellent differentiation thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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