ANTIGEN SPECIFIC TOLEROGENIC ANTIGEN PRESENTING CELLS AND RELATED USES COMPOSITIONS, METHODS AND SYSTEMS

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专利权人:

发明人:

申请号：

EP10754751.5

公开号：

EP2477636A1

申请日:

2010.09.17

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention relates to the use of tolerogenic dendritic cells in treatment and/or prevention of atherosclerosis. The cells have preferably been pretreated with at least one cytokine selected from the TGF-beta superfamily, such as TGF-beta-2, and/or with interleukin-10. Preferably, the cells have also been loaded with an autoantigen of atherosclerosis, such as the LDL protein, ApoB100 or a peptide thereof.

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