The present disclosure provides a stereotactic device including a basement, a first horizontal displacement module, a second horizontal displacement module, a supporting module and an operation module. The first horizontal displacement module is disposed on the basement and is reciprocally movable along a first moving direction. The second horizontal displacement module is disposed on the basement and is reciprocally movable along a second moving direction. The supporting module is disposed on the second horizontal displacement module. The supporting module includes a supporting unit and a holding unit. The operation module is disposed on the supporting module. The operation module includes a support unit, a rotation unit, a transmission unit and a sliding unit. In conclusion, the present disclosure improves the overall operational dexterity and efficiency while preserving the precision.本發明公開一種立體定向裝置,其包括一基座、一第一水平位移模組、一第二水平位移模組、一承載模組以及一操作模組。第一水平位移模組設置於基座上且能沿著一第一移動方向往復移動。第二水平位移模組設置於第一水平位移模組上且能沿著一第二移動方向往復移動。承載模組設置於第二水平位移模組上。承載模組包括一承載單元以及一握持單元。操作模組設置於承載模組上。操作模組包括一支架單元、一旋轉單元、一傳動單元以及一滑動單元。藉此,本發明提高了整體移動的靈敏度並保持精確度。