Apparatus, methods and kits are provided for X-ray guided focused ultrasound treatment that simplify focused ultrasound treatment. The apparatus comprises an arm, a cradle, a focused ultrasound (FUS) transducer having a central axis that is affixed in to the cradle and configured to transmit an ultrasound therapeutic energy beam to a treatment location within a patient and an imaging workstation connected to an X-ray imaging unit. The FUS is further connected to a controller to control application of the FUS. The kits are utilizing coupling member (s).