EDWARDS, Eric S.,EDWARDS, Evan T.,LICATA, Mark J.,BLONDINO, Frank E.
申请号:
EP12751771
公开号:
EP2680899A4
申请日:
2012.02.27
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Medicament delivery devices for administration of opioid antagonists are described herein. In some embodiments, an apparatus includes a housing, a medicament container disposed within the housing and an energy storage member disposed within the housing. The medicament container is filled with a naloxone composition that includes naloxone or salts thereof, a tonicity-adjusting agent, and a pH adjusting agent, whereby the osmolality of the naloxone composition ranges from about 250-350 mOsm and the pH ranges from about 3-5. The energy storage member is configured to produce a force to deliver the naloxone composition.