Edwards, Evan T.,Edwards, Eric S.,Licata, Mark J.,Blondino, Frank E.
申请号:
AU2011218756
公开号:
AU2011218756A1
申请日:
2011.09.05
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2011218756A120120913.pdf#####Attorney Docket No. INTJ-008/OOUS - 306456-2115 Abstract Medicament delivery devices for administration of opioid antagonists are described herein. In some embodiments, an apparatus includes a housing, a medicament container disposed within the housing and an energy storage member disposed within the housing. The medicament container is filled with a naloxone composition that includes naloxone or salts thereof, a tonicity-adjusting agent, and a pH adjusting agent, whereby the osmolality of the naloxone composition ranges from about 250-350 mOsm and the pH ranges from about 3-5. The energy storage member is configured to produce a force to deliver the naloxone composition. 731147 1000 1570 F1 1400 1420 1110 __ FIG.1 2000 2570 2110 F22410 2420 2400FlG.2