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pharmaceutical composition for prevention or treatment of pancreatic cancer comprising a gossypol and a phenformin
专利权人:
국립암센터
发明人:
김수열,우상명,이우진,김태현,박상재,이주희,한성식,홍은경
申请号:
KR1020180021189
公开号:
KR1020111050000B1
申请日:
2018.02.22
申请国别(地区):
KR
年份:
2019
代理人:
摘要:
The present invention provides a pharmaceutical composition comprising gosypol and phenformin, which may exhibit a synergistic effect in the treatment of pancreatic cancer. In the concentration range provided by the present invention, when Gopsipol and phenformin are mixed and applied to the treatment of pancreatic cancer, co-administration of Gosipol or phenformin alone is performed by concomitant administration even in a concentration range where a significant pancreatic cancer treatment effect cannot be obtained. The pancreatic cancer killing effect is significantly increased to enable effective pancreatic cancer treatment. In addition, in addition to gosipol and phenformin, when the anticancer agent is mixed and applied to the treatment of pancreatic cancer, the cancer cell killing effect may be significantly increased, and thus effective pancreatic cancer treatment is possible.본 발명은 췌장암 치료에 있어서 시너지 효과를 나타낼 수 있는, 고시폴 및 펜포르민을 포함하는 약학적 조성물을 제공하는 것이다. 본 발명에서 제공하는 농도 범위로 고시폴 및 펜포르민을 혼합하여 췌장암 치료에 적용하면, 고시폴 또는 펜포르민을 단독 투여에 의해 유의적인 췌장암 치료 효과를 얻을 수 없는 농도 범위에서도 병용 투여에 의해 췌장암 사멸 효과가 현저하게 증가하여 효과적인 췌장암 치료가 가능하다. 또한, 고시폴 및 펜포르민에 더하여 항암제를 혼합하여 췌장암 치료에 적용하면, 암세포 사멸 효과가 현저히 증가할 수 있으므로, 효과적인 췌장암 치료가 가능하다.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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