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New bicyclic pyridine derivatives
- 专利权人:
- F. Hoffmann-La Roche AG
- 发明人:
- BUETTELMANN, Bernd,CONTE, Aurelia,KUEHNE, Holger,KUHN, Bernd,NEIDHART, Werner,OBST SANDER, Ulrike,RICHTER, Hans
- 申请号：
- ES13750576
- 公开号：
- ES2596243T3
- 申请日:
- 2013.08.19
- 申请国别(地区):
- ES
- 年份:
- 2017
- 代理人:
- 摘要：
- Compounds of the formula (I) ** Formula ** in which: R 1 is alkyl, haloalkyl, cycloalkyl, substituted cycloalkyl, alkoxy, alkoxyalkyl, alkoxyalkoxy, alkoxycarbonyl, alkoxycarbonylalkyl, carboxy, carboxyalkyl, haloalkyl, haloalkoxy, haloalkoxyalkyl, cycloalkoxy substituted cycloalkoxy, cycloalkoxy alkyl, substituted cycloalkoxyalkyl, hydroxyalkyl, aryl, substituted aryl, heterocycloalkyl, substituted heterocycloalkyl, heterocycloalkoxy, substituted heterocycloalkoxy, heterocycloalkylalkoxy, heterocycloalkylalkoxy substituted, heteroaryloidocarbonidoalkyloidocarbonyloidocarbonyl, substituted alkyloidocarbonyl, substituted alkylaryloxycarbonyl, alkyloidocarbonyl, substituted cycloalkyloidocarbonyl, substituted cycloalkyloidocarbonyl, substituted cycloalkyloidocarbonyl, substituted cycloalkyloidocarbonyl, substituted cycloalkyloidocarbonyl, substituted cycloalkyloidocarbonyl, substituted cycloalkyloidocarbonyl, substituted cycloalkyloidocarbonyl, substituted cycloalkyloidocarbonyl, substituted cycloalkyloidocarbonyl, substituted cycloalkoxy, substituted, substituted cycloalkoxyalkyl, substituted aryl, substituted heterocycloalkyl, substituted heterocycloalkoxy, substituted heterocycloalkylalkoxy and substituted heteroaryl are substituted one to three times by substituents independently selected from hydroxy, oxo, halo eno, alkyl, cycloalkyl, haloalkyl, alkylcycloalkyl, cycloalkylalkyl, alkylcycloalkylalkyl, hydroxyalkyl, alkylsulfonyl, alkylsulfonylalkyl, alkoxycarbonyl, alkoxy and alkoxyalkyl and said substituted amino and substituted aminocarbonyl are substituted on the one or two substituted alkyl atoms by cycloalkyl, haloalkyl, alkylcycloalkyl, cycloalkylalkyl, alkylcycloalkylalkyl, hydroxyalkyl and alkoxyalkyl； R2 is -COOH, tetrazol-5-yl, [1,3,4] oxadiazol-2-on-5-yl, [1,3,4] oxadiazol-2-thion-5-yl, [1,2, 4] oxadiazol-5-on-3-yl, [1,2,4] oxadiazol-5-thion-3-yl, [1,2,3,5] oxathiadiazol-2-oxide-4-yl, [1 , 2,4] thiadiazol-5-on-3-yl, isoxazol-3-ol-5-yl, 5- alkylisoxazol-
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
