James D. Rodgers,Stacey Shepard,Lixin Shao,Joseph Glenn
申请号:
US16047544
公开号:
US10640506B2
申请日:
2018.07.27
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides cyclobutyl substituted pyrrolopyrimidines and pyrrolopyridines of Formula I:wherein X, Y, Z, L, A, R5, n and m are defined above, as well as their compositions and methods of use, that modulate the activity of Janus kinases (JAKs) and are useful in the treatment of diseases related to the activity of JAKs including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.