RODGERS, JAMES D.,SHEPARD, STACEY,ZHU, WEN-YU,SHAO, LI-XIN,GLENN, JOSEPH
申请号：
TW100142377
公开号：
TW201249845A
申请日:
2011.11.18
申请国别(地区):
TW
年份:
2012
代理人:
摘要：
The present invention provides cyclobutyl substituted pyrrolopyrimidines and pyrrolopyridines of Formula I: wherein X, Y, Z, L, A, R5, n and m are defined above, as well as their compositions and methods of use, that modulate the activity of Janus kinases (JAKs) and are useful in the treatment of diseases related to the activity of JAKs including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.
