Pharmaceutical composition comprising fusion peptide targeting cancer cells and tumor associated macrophages for treating cancer and inhibiting metastasis
TECHNICAL FIELD The present invention relates to a pharmaceutical composition for inhibiting cancer and tumor metastasis, which comprises a fusion peptide as an active ingredient. More particularly, the present invention relates to a pharmaceutical composition for inhibiting cancer and tumor metastasis by overexpressing an IL-4 receptor, TAM) at the same time, thereby exhibiting an excellent anticancer effect and a cancer metastasis inhibiting effect. The pharmaceutical composition of the present invention simultaneously targets and kills tumor cells and tumor associated macrophages, and has anticancer effects as well as suppression of metastasis. In addition, the fusion peptide of the present invention can be used in combination with a conventional anti-cancer drug to reduce side effects of conventional anti-cancer effects and to inhibit cancer and metastasis.본 발명은 융합 펩타이드를 유효성분으로 포함하는 항암 및 암 전이 억제용 약학적 조성물에 관한 것으로, 보다 상세하게는, 본 발명은 IL-4 수용체를 과발현하는 암세포 및 종양관련 대식세포(tumor associated macrophage,TAM)를 동시에 표적함으로써 우수한 항암효과 및 암 전이 억제효과를 나타내는 약학적 조성물에 관한 것이다. 본 발명의 약학적 조성물은 종양세포 및 종양관련 대식세포(tumor associated macrophage)를 동시에 표적하여 사멸시켜 항암 효과뿐만 암전이 억제 효과를 동시에 가지고 있다. 또한 본 발명의 융합 펩타이드는 기존 항암약물과 병용투여 기존 항암효과의 부작용을 감소시키면서 항암 및 암전이 억제효과를 나타낸다.
