Thomas Daniel Aicher,Fernando Padilla,Peter L. Toogood,Shoujun Chen
申请号:
US15551132
公开号:
US20180093978A1
申请日:
2016.02.26
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention provides indazolyl thiadiazolamines and related compounds, pharmaceutical compositions, methods of inhibiting Rho-associated protein kinase, and methods of treating inflammatory disorders, immune disorders, fibrotic disorders, and other medical disorders using such compounds. An exemplary indazolyl thiadiazolamine compound is an N-(5-[5-[(1H4ndazol-5-yl)amino]-1,3,4-thiadiazol-2-yl]pyridin-3-yl)acetamide compound.