A method for preventing and/or treating lipid metabolism disorders and related diseases thereof, comprising administering an effective amount of plasminogen to a subject prone to suffer or suffering lipid metabolism disorders and related diseases thereof to reduce the abnormal deposition of lipid in different parts of a body, thereby implementing the prevention and/or treatment of lipid metabolism disorders and related diseases or complications thereof.本發明涉及一種預防和/或治療脂肪代謝紊亂及其相關病症的方法,包括給藥易患或患有脂肪代謝紊亂及其相關病症的受試者有效量的纖溶酶原,以消減脂肪在身體各部位的異常沉積,從而實現預防和/或治療脂肪代謝紊亂、其相關病症或併發症的目的。