The present invention relates to a composition for treating or preventing interstitial cystitis which contains an extract of a herbal mixture including cornus fruit, Reynoutria japonica, Rubus coreanus fruit, lonicer aflower, cuscuta seeds, Curcuma Longa, and lindera roots. The extract of the herbal mixture relieves the inflammation and pain in cystitis, and is capable of being used as an excellent interstitial cystitis remedy. [Reference numerals] (AA) (First step) step of producing a herbal mixture by mixing 100 wt% of cornus fruit, 50-200 wt% of reynoutria japonica, 50-200 wt% of rubus coreanus fruit, 50-200 wt% of lonicer aflower, 20-80 wt% of cuscuta seeds, 20-80 wt% of curcuma longa, and 20-80 wt% of lindera roots； (BB) (Second step) step of mixing the 2-10 times extraction solvent of the total weight of the herbal mixture in the herbal mixture of the first step and extracting it at 70-100°；C for 1-10 hours； (CC) (Third step) step of removing solids contents of the extract in the second step and collecting filtrate본 발명은 산수유, 호장근, 복분자, 금은화, 토사자, 울금 및 오약의 생약 혼합물의 추출물을 함유하는 간질성 방광염의 예방 또는 치료용 조성물에 관한 것으로서, 상기 생약 혼합물의 추출물은 방광의 염증 및 통증을 완화하여 우수한 간질성 방광염 치료제로 사용될 수 있다.
