The Government Of The U.S.A; As Represented By The Secretary; Dept. Of Health And Human Services
发明人:
申请号：
EP12702953.6
公开号：
EP2670843A1
申请日:
2012.02.02
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
The present invention provides methods and compositions for inducing an immune response that confers dual protection against infections by either or both of a rabies virus and a filovirus, and/or which can be used therapeutically for an existing infection with rabies virus and/or a filovirus to treat at least one symptom thereof and/or to neutralize or clear the infecting agents. In particular, the present invention provides a recombinant rabies virus vector omprising a nucleotide sequence encoding at least one filovirus glycoprotein or an immunogenic fragment thereof, as well as pharmaceutical compostions comprising the vaccine vectors.
