FILM CONTENANT UNE BASE LIBRE TADALAFIL, FORME GALÉNIQUECONTENANT UN POLYMÈRE À BASE DE POLYÉTHYLÈNE GLYCOL ET/OU UN POLYMÈRE À BASE DE PYRROLIDONE DE VINYLE, COMME STABILISATEUR DE DISPERSION
JEON, HONG RYEOL,KWON, DO-WOO,LEE, BONG-SANG,PARK, SU-JUN,CHA, BONG-GEUN,KIM, JUN-KI,HAN, JIYEONG,KIL, MYEONGCHEOL
申请号：
EP14782874
公开号：
EP2985020A4
申请日:
2014.04.11
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
The present disclosure relates to a film formulation for oral administration, containing tadalafil free base and a method of preparing the same, and a film may be provided with maximized dispersion stability of tadalafil free base in the film by the addition of a dispersion stabilizing agent in small amounts without unique fragrance or favor that may appear when other dispersion stabilizing agents known in the art are used, and an extremely low likelihood that a reagglomeration phenomenon of tadalafil free base particles will occur, and an amount of bubbles generated may be significantly reduced during a production process.
