COMPOSITION POUR UNE UTILISATION DANS L'AUGMENTATION DE L'EFFICACITE DE LA PRISE DE GREFFE DE CELLULES SOUCHES HEMATOPOIETIQUES APRES UNE TRANSPLANTATION

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专利权人:

SCIPHARM SARL

发明人:

FREISSMUTH, MICHAEL,ZEBEDIN-BRANDL, EVA-MARIA,KAZEMI, ZAHRA

申请号：

CA2973146

公开号：

CA2973146A1

申请日:

2016.01.27

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The present invention provides the new use of composition comprising at least one inhibitor of dipeptidyl peptidase IV (DPP-IV) for increasing migration and homing of haematopoetic progenitor cells in stem cell transplanted recipients, wherein said haematopoetic stem and/or progenitor cells had been treated in vitro with an engraftment enhancing compound, specifically with a prostacyclin analogue and a cAMP enhancer before transplantation.

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