COMPOSITION FOR USE IN INCREASING ENGRAFTMENT EFFICACY OF HAEMATOPOETIC STEM CELLS AFTER TRANSPLANTATION

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专利权人:

SCIPHARM SÀRL

发明人:

FREISSMUTH, Michael,ZEBEDIN-BRANDL, Eva-Maria,KAZEMI, Zahra

申请号：

SG11201705812S

公开号：

SG11201705812SA

申请日:

2016.01.27

申请国别(地区):

SG

年份:

2017

代理人:

摘要：

The present invention provides the new use of composition comprising at least one inhibitor of dipeptidyl peptidase IV (DPP-IV) for increasing migration and homing of haematopoetic progenitor cells in stem cell transplanted recipients, wherein said haematopoetic stem and/or progenitor cells had been treated in vitro with an engraftment enhancing compound, specifically with a prostacyclin analog and a cAMP enhancer before transplantation.

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