Systems, devices and methods for analyzing the movement, orientation, and location of patients and other users within a hospital, nursing home, or other setting where patient monitoring is desired. One or more sensors or markers are positioned on the body of the user, and a plurality of readers or transceivers in known relative location within the patient care environment detect or communicate with the sensors or markers to identify user location. Location sensing techniques include multi-angulation, multi-lateration, scene analysis (such as visual image analysis), or proximity. Analysis techniques used include time-of-flight analysis, signal strength analysis, image, and video analysis.