A closure (170) for a vial (100) comprising a vial container (110) and a sealing (280). The closure (170) comprises a body (180), at least one holding element (190) adapted to hold the closure (170) permanently secure on the vial container (110) and such that the sealing (280) is adapted to provide a tight connection between the vial container (110) and the body (180), a penetrable portion (290) adapted to allow a liquid transfer is disclosed and a cap (200) adapted to provide a germ free protection of the penetrable portion (290), wherein the body (180) and the penetrable portion (290) are integrally formed.Further, a vial (100) with such a closure (170), a method for closing a vial container (110) with such a closure (170) and a method for manufacturing such a closure (170) are disclosed.
