A method for removing a fluid medium from a container. The method comprises providing a removal device with a closed-off, sterilizable interior, with a needle element being held in the interior, the interior being closed off by a perforable sealing element providing the container which contains the fluid medium, the container having a container wall with a perforable section connecting the removal device and the container, the perforable section and the perforable sealing element being interconnected such that a protected region is created between the perforable section and the perforable sealing element, the protected region being closed off with respect to the surroundings in a substantially germ-free fashion as a result of the connection and perforating the perforable sealing element and the perforable section by means of the needle element, the needle element penetrating the protected region.
