A manufacturing method for medical equipment wherein an electron beam is irradiated on a titanium or titanium alloy substrate surface that has at least been machined, and the platelet adhesion of a surface which is in contact with blood is reduced; and a manufacturing method for medical equipment that uses a specific pre-processing method and an electron beam irradiation method to reduce the platelet adhesion of a surface which is in contact with blood, and which suppresses the formation of minute depressions (craters) in the surface, which can occur due to the irradiation of an electron beam.