THROUGH ITS CONSTITUENT UNIVERSITY IN DILIMAN QUEZON CITY; PHILIPPINES;THE UNIVERSITY OF THE PHILIPPINES
发明人:
ANACLETO M. ARGAYOSA,CHELO S. PASCUA,FLORENTINO O. SUMERA,JOHN ANTHONY DL. YASON,ALPHA RAE M. ESPIGAR
申请号：
PH12013000256
公开号：
PH12013000256B1
申请日:
2013.08.30
申请国别(地区):
PH
年份:
2015
代理人:
摘要：
An oral vaccine comprising a pathogen in a non-infective state and a layered silicate, whereby the layered silicate is adsorbed on the pathogen thereby encapsulating the pathogen, is described. The layered silicate is preferably montmorillonite, bentonite or kaolinite, or a mixture thereof. The pathogen may be a bacteria, or Aeromonas hydrophila in particular, or a virus. Also described is a method of enhancing an immune response from a subject, comprising orally administering the oral vaccine to the subject, as well as a method for the production of the oral vaccine, comprising exposing a pathogen to an agent that renders the pathogen non-infective and encapsulating the pathogen with a layered silicate.
