NOVEL PYRIMIDINE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER AND INFLAMMATORY DISEASES
Kwangho LEE,Gildon CHOI,Na Ri LEE,Sang Jun PARK,Myoung Eun JUNG,Seong Jin KIM,Kyung-Min YANG,Jihee LEE
申请号：
US16347480
公开号：
US20190284143A1
申请日:
2017.11.01
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to novel pyrimidine compounds, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient for preventing or treating cancer and inflammatory disease. The novel pyrimidine compounds according to the present invention remarkably inhibits activity of DRAK that inhibits signal systems of TGF-β, which is known to suppress cancer growth, and thus the novel pyrimidine compounds can be used as a pharmaceutical composition for preventing or treating cancer and can be used as a pharmaceutical composition for preventing or treating inflammatory disease.
