This multi-articulated manipulator is rich in reliability and follow-up property in medical applications. The multi-articulated manipulator is composed of more than one hollow outer shell, joint members to connect the outer shells each other, a grasping member fastened for rocking movement to the foremost outer shell, and a power transmission shaft to actuate the grasping member and the outer shell in a bending manner independently from each other. The power transmission shaft is composed of a universal join allowed to bend independently from each other and transmit the rotating torque, and a transmission shaft capable of making expansion and shrinkage and able to transmit rotating torque. The power transmission shaft at the foremost end thereof has male threads mating with the nut made at the boss portion inside the outer shell.
