The present invention relates to an infusion connecting apparatus and a manufacturing method thereof, wherein the apparatus is characterized by comprising: a vial-type injection container wherein a resin cap with an open center is integratedly capped with an opening of a plastic bottle and an injection is filled a two-way type bottle opening medicine container made of glass of glass or plastic, which contains lyophilized powder or an aqueous medicine in the inside thereof and then is capped with a rubber plug and air-tightly sealed with an aluminium ring a boring needle guide unit wherein a fluid opening and closing cap, into which the resin cap of the injection container having a built-in packing is forcefully inserted to be air-tightly integrated, is assembled with a longitudinal hollow unit where a boring needle pressurizing member is contained, and thereby, being integratedly assembled with a radio-frequency welding and a boring needle transfer communicating unit on which a screw thread is formed in the hollow unit rotated by combining a taper binding convex unit and a taper concave unit of the boring needle guide unit on which a screw protrusion unit containing the boring needle pressurizing member to have the boring needle is projected. Additionally, the apparatus has a half-divided stopper protrusion is formed on the outer peripheral surface of the screw thread of the other end of the taper binding convex unit of the boring needle transfer communicating unit, and the two-way type bottle opening medicine container is injectedly contained in a vial cartridge of the connector including the vial cartridge integratedly formed on the outer peripheral surface of the stopper protrusion. The present invention is used in bottle drop injection by easily diluting lyophilized powder of various medicinal fluids in various injections in a vial or bag form.COPYRIGHT KIPO 2014본 발명은 수액연결장치 및 그 제조방법에 관한 것으로, 중앙이 개방된 수지캡이 플라스틱제 병구에 일체로 캡핑되고 주사액이 봉입되는 바이알형 주사액용기와 유리 또는 플라스틱제로 내부에