Pure pharmacological synthesis consisting of EC145 (Vintafolida) and a volume agent; methods for the production of this Liofilizada pharmacological synthesis method, including a tampon; pharmacological products; dosage units; and methods for the treatment of tumors with leaf receptors Functional activities.
The invention described herein pertains to a solid pharmaceutical composition comprising EC145 for reconstitution to provide a solution for intravenous injection, particularly to a lyophilized solid pharmaceutical composition comprising EC145 which has adequate stability for storage at ambient temperature and which is capable of redissolving in an aqueous diluent prior to administration, as well as a process for its manufacture, drug products comprising the composition and methods for using the composition for treating cancer.COMPOSICION FARMACEUTICA SOLIDA QUE COMPRENDE EC145 (VINTAFOLIDA) Y UN AGENTE DE VOLUMEN; METODO PARA PRODUCIR ESTA COMPOSICION FARMACEUTICA LIOFILIZADA QUE COMPRENDE OPCIONALMENTE UN TAMPON; PRODUCTO FARMACOLOGICO; UNIDAD DE DOSIFICACION; Y METODO PARA TRATAR UN TUMOR PORTADOR DE RECEPTORES DE FOLATO FUNCIONALMENTE ACTIVOS.