抗血栓性コーティング剤及び医療用具
- 专利权人:
- 独立行政法人国立循環器病研究センター
- 发明人:
- 中山 泰秀,水野 敏秀,巽 英介,妙中 義之,根本 泰
- 申请号:
- JP2007079375
- 公开号:
- JP5146945B2
- 申请日:
- 2007.03.26
- 申请国别(地区):
- JP
- 年份:
- 2013
- 代理人:
- 摘要:
PROBLEM TO BE SOLVED: To provide releasing material for polysaccharides or their salt with 1,3-&beta-crosslink type D-glucose as a repeating unit introducing a sulfate group which has temperature responsiveness that is hydrophilic at a temperature lower than a prescribed temperature T lower than a living body temperature and becomes hydrophobic at a higher temperature than the prescribed temperature.
SOLUTION: The releasing material for polysaccharides or their salt with 1,3-&beta-crosslink type D-glucose as a repeating unit has introduced the sulfate group comprising a polymer material for carrying the polysaccharides or their salt with 1,3-&beta-crosslink type D-glucose introducing the sulfate group as the repeating unit. The polymer is hydrophilic at a temperature lower than a prescribed temperature T which is lower than a living body temperature and is hydrophobic at a temperature higher than the prescribed temperature T. The polymer material is obtained by block polymerization of N-isopropylacrylamide to a homopolymer comprising a branch polymer made by light illumination living polymerization of a vinyl monomer using a compound having 3 or more groups of N, N-dialkyl-dithiocarbamylmethyl molecule in an identical molecule as an iniferter.
COPYRIGHT: (C)2009,JPO&INPIT
- 来源网站:
- 中国工程科技知识中心
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