Dong Wook KANG,Jee Woo LEE,Young Ho KIM,Hee KIM,Hee Jin HA,Eun Joo NAM,Chan Mi JOUNG
申请号：
US13489261
公开号：
US20120245165A1
申请日:
2012.06.05
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to the novel benzofuran derivatives, the preparation thereof and the composition comprising the same. The benzofuran derivatives of the present invention showed potent inhibiting activity of beta-amyloid aggregation and cell cytotoxicity resulting in stimulating the proliferation of neuronal cells as well as recovering activity of memory learning injury caused by neuronal cell injury using transformed animal model with beta-amyloid precursor gene, therefore the compounds can be useful in treating or preventing cognitive function disorder.
