Composés de métallocène et molécules marquées comprenant ceux-ci pour l'imagerie in vivo

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专利权人:

Aptenia S.R.L.

发明人:

申请号：

EP13158111.8

公开号：

EP2774930A1

申请日:

2013.03.07

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The present invention concerns compounds and methods of labeling peptides or other molecules with 18F or 19F or any other suitable radionuclide of use, for example, in PET or NMR in vivo imaging.A targeting molecule such as a protein or a peptide is linked to a substituted metallocene complex which is reacted with the 18F or 19F shortly before performing the PET or NMR in vivo imaging on the patient. The labeled molecule is then used for targeting a cell, tissue, organ or pathogen to be imaged or detected.

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中国工程科技知识中心

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http://www.ckcest.cn/home/