Jose Baselga;Carlos Garcia-Echeverria;Russillo Michelangelo;Wolfgang Hackl;Violeta Serra Elizalde;Serena Di Cosimo;Sauveur-Michel Maira
发明人:
Jose Baselga,Serena Di Cosimo,Carlos Garcia-Echeverria,Wolfgang Hackl,Sauveur-Michel Maira,Russillo Michelangelo,Violeta Serra Elizalde
申请号：
US13319536
公开号：
US20120059005A1
申请日:
2010.05.12
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to a pharmaceutical combination which comprises (a) a phosphoinositide 3-kinase inhibitor compound and (b) an insulin sensitivity enhancer compound for the treatment of a proliferative disease, especially a solid tumor disease； a pharmaceutical composition comprising such a combination； the use of such a combination for the preparation of a medicament for the treatment of a proliferative disease； a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use； and to a method of treatment of a warm-blooded animal, especially a human.
