Carlos Garcia Echeverria,José Baselga Torres,Michelangelo Russillo,Sauveur-Michel Maira,Serena Di Cosmo,Violeta Sreea Elizalde,Wolfgang Hackl
申请号:
BRPI1010979
公开号:
BRPI1010979A2
申请日:
2010.05.12
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The invention relates to a pharmaceutical combination which comprises (a) a phosphoinositide 3-kinase inhibitor compound and (b) an insulin sensitivity enhancer compound for the treatment of a proliferative disease, especially a solid tumor disease; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of a proliferative disease; a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use; and to a method of treatment of a warm-blooded animal, especially a human.