Latent Human Immunodeficiency Virus reactivation

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专利权人:

The UAB Research Foundation

发明人:

Kutsch, Olaf,Niederweis, Michael,Wolschendorf, Frank,Duverger, Alexandra,Wagner, Frederic

申请号：

AU2011255621

公开号：

AU2011255621A1

申请日:

2011.05.18

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

Provided herein are methods or reactivating a latent Human Immunodeficiency Virus (HIV) infection in a cell. The methods comprise modulating a level of NF-κB activity in the cell by contacting the cell with an agent that produces a transient first increase in the level of NF-κB activity without a second delayed increase in NF-κB activity. Optionally, a second agent is used to prime the reactivation. Also provided herein is an isolated

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