Walter Bottje;Young Min Kwon;Sherryll Layton;Luc Berghman;Kimberly Cole;Mandy Cox;Billy Hargis
发明人:
Walter Bottje,Billy Hargis,Luc Berghman,Young Min Kwon,Kimberly Cole,Mandy Cox,Sherryll Layton
申请号：
US12441851
公开号：
US08604178B2
申请日:
2007.09.18
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided herein are Salmonella enteritidis 13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response against Influenza A and methods of reducing morbidity associated with an Influenza A infection. Methods of enhancing an immune response to a vaccine vector by expressing a polypeptide of CD 154 capable of binding CD40 are also disclosed. Methods of developing a bacterial vaccine vector are disclosed. Methods of generating scarless site-specific mutations in a bacterium are also disclosed.
