The Texas A&M University System;THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
发明人:
BOTTJE, WALTER,HARGIS, BILLY,BERGHMAN, LUC,KWON, YOUNG MIN,COLE, KIMBERLY,COX, MANDY,LAYTON, SHERRYLL
申请号:
PL07842706
公开号:
PL2066339T3
申请日:
2007.09.18
申请国别(地区):
PL
年份:
2015
代理人:
摘要:
Provided herein are Salmonella enteritidis 13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response against Influenza A and methods of reducing morbidity associated with an Influenza A infection. Methods of enhancing an immune response to a vaccine vector by expressing a polypeptide of CD154 capable of binding CD40 are also disclosed. Methods of developing a bacterial vaccine vector are disclosed. Methods of generating scarless site-specific mutations in a bacterium are also disclosed.