The purpose of the present invention is to provide: a heat shock protein expression inducer capable of inducing the in-vivo expression of HSP; food, drink, a pharmaceutical product, and a cosmetic containing the HSP expression inducer; and an HSP expression inducing method. Compounds derived from a specific plant such as Zerumbone or an analogue thereof exert an excellent action of inducing the expression of heat shock proteins in vivo, and can be used as the active ingredient for a heat shock protein expression inducer.本發明之目的在於提供一種:可於活體內誘導HSP表現之熱誘蛋白表現誘導劑;含有HSP表現誘導劑之飲食品、醫藥品、化妝品;及,HSP表現誘導方法。解決手段則在於:花薑酮(Zerumbone)或其類似物等之源自特定植物的化合物係於活體內具有優異之誘導熱誘蛋白表現之作用,而可作為熱誘蛋白表現誘導劑之有效成分予以利用。