RÉCEPTEUR HÉTÉRODIMÈRE SOLUBLE DE CELLULES T, ET SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION

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专利权人:

Guangzhou Xiangxue Pharmaceutical Co. Ltd.

发明人:

申请号：

EP15857032.5

公开号：

EP3216801A1

申请日:

2015.11.04

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Provided is a high-stability T cell receptor (TCR). The TCR comprises (i) the whole or a part of TCRα chain except a transmembrane domain thereof, and (ii) the whole or a part of TCRβ chain except a transmembrane domain thereof, both the (i) and the (ii) comprising a functional variable domain and at least a part of a constant domain of a TCR chain. An artificial interchain disulfide bond links the constant domains of the TCRα and β chains, and a Tm value of the T cell receptor is greater than or equal to 45°C.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/