Antonio Oliviero,Juan de Los Reyes Aguilar Lepe,Mario Rotondi,Eduardo Molina Holgado,Luca Chiovato,Guglielmo Foffani,Laura Mordillo Mateos,Angel Lozano Sicilia,Daniel Garcia Ovejero,Angel Arevalo Mart
申请号:
US14978088
公开号:
US20160106752A1
申请日:
2015.12.22
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Use of a CB1 receptor antagonist and/or inverse agonist, preferably rimonabant, for the preparation of drugs useful for increasing motor neuron excitability in the cerebral cortex and/or in the brain stem and/or at the spinal level, as well as a method for increasing motor neuron excitability through the administration of a CB1 antagonist/ inverse agonist receptors, and to the use of a pharmaceutical composition which comprises a CB1 receptor antagonist and/or inverse agonist, preferably rimonabant, for increasing motor neuron excitability in the cerebral cortex and/or in the brain stem and/or at the spinal level.