Antonio Oliviero,Juan de los Reyes Aguilar Lepe,Mario Rotondi,Eduardo Molina Holgado,Luca Chiovato,Guglielmo Foffani,Laura Mordillo Mateos,Ángel Lozano Sicilia,Daniel García Ovejero,Ángel Arévalo Mart
申请号:
US13144078
公开号:
US20120015945A1
申请日:
2010.01.11
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Use of a CB1 receptor antagonist and/or inverse agonist, preferably rimonabant, for the preparation of drugs useful for increasing motor neuron excitability in the cerebral cortex and/or in the brain stem and/or at the spinal level, as well as a method for increasing motor neuron excitability through the administration of a CB1 antagonist/inverse agonist receptors, and to the use of a pharmaceutical composition which comprises a CB1 receptor antagonist and/or inverse agonist, preferably rimonabant, for increasing motor neuron excitability in the cerebral cortex and/or in the brain stem and/or at the spinal level.