Rodrigo de Azeredo Siqueira;Núbia Boechat;Jorge Carlos Santos Da Costa;Marco Aurélio Martins
发明人:
Marco Aurélio Martins,Jorge Carlos Santos Da Costa,Núbia Boechat,Rodrigo de Azeredo Siqueira
申请号:
US11570234
公开号:
US08163803B2
申请日:
2005.06.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to lidocaine derived compounds, which present less anesthetic activity than lidocaine itself, but with more anti-inflammatory and spasmolytic activity than said lidocaine as well as pharmaceutical compositions with at least one of these compounds or a salt of those as active principle and to the use of such compositions to treat, prevent or inhibit atopic diseases including asthma, rhinitis, allergic urticaria, chronic lung inflammation associated with eosinophilia, following the example of atopic asthma and chronic intestinal inflammation, as colitis for instance. The pharmaceutical composition may be available in spray form, solution, suspension, emulsion destinated to be applied by nebulization, or in any of the pharmaceutical available forms for oral or injectable use.