Jean-Paul CASTAIGNE,Michel Demeule,Christian Che,Anthony Regina
申请号:
US14640802
公开号:
US20150174267A1
申请日:
2015.03.06
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention is directed to conjugates that include a polypeptide capable of crossing the blood-brain barrier or entering one or more cell types attached to a transport vector, i.e., a composition capable of transporting an agent (e.g., a therapeutic agent). In certain cases, the polypeptides are directly conjugated to a lipid or polymeric vector to allow targeted application of a therapeutic agent to treat, for example, a cancer, a neurodegenerative disease, or a lysosomal storage disorder.