Methods, systems, and apparatuses for measuring the efficacy of a renal denervation procedure are described. In one embodiment, a method for measuring the efficacy of a renal denervation procedure includes utilizing an ablation catheter including one or more sensors designed and configured for measuring and reporting the plasma norepinephrine level of a subject. The plasma norepinephrine levels of the subject may be measured intermittently after each individual ablation, or may be continuously monitored throughout an entire ablation procedure to provide real time plasma norepinephrine level data to the operator to assist in determining the efficacy of the procedure.
