The present invention relates to a pharmaceutical composition and health-aid food comprising an extract of plants of Suaeda spp., particularly an extract of Suaeda maritima, as an active ingredient for preventing or treating thrombosis. More particularly, the present invention relates to a pharmaceutical composition and health-aid food comprising an ethyl acetate fraction, butanol fraction or water residue of an extract of Suaeda maritima, or a combination thereof, as an active ingredient for preventing or treating/improving thrombosis through inhibition of blood coagulation and that of platelet aggregation. According to the present invention, the extract of plants of Suaeda spp., particularly an extract of Suaeda maritima, as an active ingredient of a pharmaceutical composition and health-aid food for preventing or treating thrombosis shows strong anti-thrombotic activity derived from inhibition of thrombosis-related enzyme and blood coagulation factors and inhibition of platelet aggregation functioning to trigger thrombosis, as well as shows no hematocytolytic activity to human red blood cells, has excellent heat stability, and causes no loss in the effects of inhibiting blood coagulation factors and thrombosis-related enzymes even under an acidic condition of pH 2 and in the plasma. Thus, it is expected that the extract can be used for preventing and treating thrombosis, such as ischemic stroke and cerebral hemorrhage, by improving blood flow. The active ingredient may be processed into various shapes, such as powder, pills and tablets, so that it may be administered anytime. Therefore, the present is very useful in the pharmaceutical industry and food industry.COPYRIGHT KIPO 2017본 발명은 나문재 속(Suaeda spp.) 식물의 추출물, 특히, 해홍나물(Suaeda maritima) 추출물을 유효성분으로 함유하는 혈전증의 예방 또는 치료용 약학적 조성물 및 건강 기능 식품에 관한 것으로서, 보다 구체적으로는, 해홍나물 추출물의 에틸아세테이트 분획물, 부탄올 분획물, 물 잔류물 또는 이들의 혼합물을 유효성분으로 하여 혈액 응고 저해 및 혈소판 응집 저해를 통한 혈전증의 예방 또는 치료/개선용 약학적 조성물 및 건강 기능 식품에 관한 것이다. 본 발명의 혈전증의 예방 또는 치료용 약학적
