The described embodiments relate to systems, methods, and apparatuses for reducing interference of signals transmitted by a physiological measurement device (108, 210, 312), such as an electrocardiogram device. The physiological measurement device can employ filters (308) that use coefficients to reduce time-domain differences between response signals of the physiological measurement device. The coefficients can be derived during a calibration process where each channel of the physiological measurement device is supplied a test signal (202) for identifying the channel with the slowest or most delayed response. Thereafter, when a monitor signal is compiled from response signals filtered using the coefficients, differences in timing between the response signals will not result in distortion of the monitor signal, thereby rendering the monitor signal more accurate for measurement purposes.
