The present invention relates to antibodies or antibody fragments that bind neutralize and/or inhibit Hendra or Nipah virus. The invention provides antibodies or antibody fragments that selectively bind to the F glycoprotein of Hendra or Nipah virus and pharmaceutical compositions including such antibodies and/or fragments. The invention further provides polynucleotides encoding the antibodies and fragments of the invention and host cells transformed therewith. Additionally the invention discloses prophylactic therapeutic and diagnostic methods employing the antibodies fragments polynucleotides and/or compositions of the invention.