CHUNG, JUNHO,KIM, BONGCHEOL,SEONG, JAE YOUNG,HWANG, JONG IK,JIN, JUNYEONG,LEE, JEE YOUN,CHO, EUN BEE,YUNE, TAE YOUNG
申请号：
CA3042989
公开号：
CA3042989A1
申请日:
2017.11.07
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present disclosure provides antibodies that specifically bind to human FAM19A5 and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human FAM19A5 and modulate FAM19A5 activity, e.g., inhibit, suppress, reduce, or reverse the onset of reactive gliosis and/or excessive proliferation of reactive astrocytes, utilizing such antibodies. The present disclosure also provides methods for treating disorders, such as central nervous system damage, a degenerative brain disorder, or a neuropathic pain, by administering an antibody that specifically binds to human FAM19A5.
