The present invention provides a magnetic resonance (MR) imaging system 110 that provides an image representation of at least a portion of a subject of interest 120 positioned in an examination space 116 and a target in a portion of the subject of interest 120. A hyperthermia device 111 for locally heating the zone and a control unit 126 for controlling the MR imaging system 110 and the hyperthermia device 111, the diagnostic imaging system 100 representing an image representation of the target zone, each obtained at different temperatures Is adapted to provide a diagnostic image representation of a portion of the subject 120 of interest, wherein the diagnostic image representation includes information regarding a temperature dependent change in metabolism of the subject 120 of interest. An imaging system 100 is provided. The present invention further includes a diagnostic imaging system 100 as described above, a treatment module 146 that applies treatment to a subject of interest 120 to destroy cells in the target zone, and a diagnostic image representation obtained by the diagnostic imaging system 100. And a control module 126 for controlling the treatment module 146 to apply the treatment based on the treatment system. Thus, metabolic changes in the subject of interest can be assessed to direct treatment to such areas where the cells have not yet been destroyed as desired. By comparing the above-described measurement differences between the first and second temperatures, the efficiency of the treatment can be assessed and further treatment can be adapted based on metabolic changes.本発明は、検査空間１１６に位置付けられた関心のある被検体１２０の少なくとも一部の画像表現を提供する磁気共鳴（ＭＲ）イメージングシステム１１０と、関心のある被検体１２０の一部の中のターゲットゾーンを局所的に加熱するハイパーサーミア装置１１１と、ＭＲイメージングシステム１１０及びハイパーサーミア装置１１１を制御する制御ユニット１２６と、を有し、診断イメージングシステム１００は、それぞれ異なる温度で得られたターゲットゾーンの画像表現を相関付けることによって、関心のある被検体１２０の一部の診断画像表現を提供するように適応され、診断画像表現は、関心のある被検体１２０の代謝の温度依存変化に関する情報を含む、診断イメージングシステム１００を提供する。本発明は更に、上述の診断イメージングシステム１００と、ターゲットゾーン内の細胞を破壊するために関心のある被検体１２０に処置を適用する処
