A composition for preventing hearing loss in a subject, or for obtaining at least partial restoration of hearing in a treated subject whose auditory function has been reduced before treatment. The composition comprises at least one sterol compound that induces neuronal differentiation and is contacted with at least a portion of the cochlea. [Selection] Figure 1【解決手段】対象者における難聴を予防するための、又は治療前は聴覚機能が低下していた治療対象者の聴覚の少なくとも部分的な修復を得るための組成物。該組成物は神経分化を誘導する少なくとも1つのステロール化合物を含み、蝸牛の少なくとも一部分と接触させる。【選択図】図1